Space-time dynamics is closely related to the concepts of change and process, which are inherent to our real-world world. Space-time dynamics is especially manifested when we move from a static to a dynamic representation of phenomena. Various processes taking place at different spatial and temporal scales interact with each other and lead to changes in the phenomena being modeled. There are many different approaches to conceptualizing and understanding space-time dynamics in order to understand or predict phenomena in heterogeneous application domains ranging from human activities and urban sprawl to disease spread and traffic flow. An example is the time geography approach and its variants, such as the spatiotemporal prism, to model and understand human physical activities that occur in and are simultaneously constrained by space and time. In the past, such a theoretical approach to understanding human and environmental systems that recognized the importance of individual human activities along with the geographic context has been applied to multiple scenarios, such as accessibility, transportation services, and urban mobility.